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Panama will again look to defy the odds and advance to the 2024 Copa America semifinals when they face highly-regarded Colombia in Saturday's quarterfinals. Panama, which had finished no higher than 12th at Copa America, upset the United States 2-1 in group play and defeated Bolivia 3-1 to reach the knockout stage. Colombia, meanwhile, continue to roll past the competition. With their 1-1 draw with Brazil on Tuesday, the Colombians have been unbeaten in their past 26 matches. They had won 10 in a row before the draw.

Kickoff from State Farm Stadium in Glendale, Ariz., is set for 6 p.m. ET. Colombia are listed as the -360 favorites (risk $360 to win $100) on the 90-minute money line in the latest Colombia vs. Panama odds, with Panama the +1000 underdogs. A draw is priced at +425 and the over/under for total goals scored is 2.5. Colombia are -800 to advance, while Panama are +500. Before making any Panama vs. Colombia picks, be sure to see the 2024 Copa America predictions from SportsLine soccer insider Brandt Sutton.

Sutton is a former collegiate soccer player and has been SportsLine's top soccer editor since 2017. He has followed soccer closely for much longer and factors in managerial tactics, projected lineups and past performances to make the most informed decisions possible.

Sutton finished the 2022-23 Champions League season with a 16-7 record (+8.93 units) on SportsLine's UCL pick sheet and is 25-20-2 (+3.20) in 2023-24. He also finished 2022 as SportsLine's No. 1 soccer expert with a 165-130-2 mark, returning nearly $2,200 for $100 players and is 139-136-5 since the 2022 World Cup.

Now, Sutton has broken down Panama vs. Colombia from every angle and has locked in his picks and 2024 Copa America predictions. You can head to SportsLine now to see Sutton's picks. Here are the betting lines and trends for Colombia vs. Panama:

  • Colombia vs. Panama 90-minute money line: Colombia -360, Draw +425, Panama +1000
  • Colombia vs. Panama over/under: 2.5 goals
  • Colombia vs. Panama to advance: Colombia -800, Panama +500
  • COL: Over their last seven matches, Colombia have outscored their opponents 18-5
  • PAN: Panama are outscoring their Copa America opponents 6-5 in three matches
  • Colombia vs. Panama picks: See picks here

Why you should back Colombia

Right wing Daniel Munoz has helped spark the Colombian offense, scoring two goals in the tournament. He scored at the 32nd minute in a 2-1 win over Paraguay on June 24, and followed that up with a goal in first-half extra time in a 1-1 draw with Brazil on Tuesday. Since joining the national team in 2021, he has registered three goals in 30 appearances. He is a member of Crystal Palace of the English Premier League.

Also boosting the offense is team captain James Rodriguez. The 32-year-old midfielder has been with the national team since 2011, and has scored 27 times in 103 matches. His professional resume is equally as impressive, having played for four seasons in Spain's La Liga for Real Madrid, where he scored 29 goals in 85 appearances. He currently is a member of Sao Paulo of Brazil's Serie A team. See which team to pick here.

Why you should back Panama

Midfielder Cesar Yanis has already made his mark at Copa America 2024. He scored in extra time to help secure the 3-1 win over Bolivia on Monday. Yanis, who joined the national team in 2020, has scored four goals in 48 appearances. He currently plays professionally in Spain for Zamora, on loan from Costa del Este. Yanis has 10 goals in 115 professional matches.

Also helping the offense is forward Jose Luis Rodriguez, who has been a member of the Panamanian team since 2018. In 49 appearances for the national team, Rodriguez has recorded six goals, including a pair last month in 2026 FIFA World Cup qualifying. He scored the second goal of a 2-0 win over Guyana on June 6, and followed that up with a goal in a 3-1 victory over Montserrat. He will be playing professionally for Red Star Belgrade in the Serbian SuperLiga later this year. See which team to pick here.

How to make Panama vs. Colombia picks

Sutton has broken down Colombia vs. Panama from every possible angle and is leaning Over on the goal total. He also has locked in a plus-money best bet. He's sharing his 2024 Copa America picks and analysis only at SportsLine.

What is the best bet for Colombia vs. Panama? Visit SportsLine now to see which wagers in have all the value, all from the proven soccer expert who has his finger on the pulse of the game all over the world, and find out.

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